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Consider Digestive Aids: Over-the-counter medications like simethicone may help relieve gas and bloating

A: B12 toxicity is extremely rare because excess amounts are eliminated through urine

Nausea, constipation, and reduced appetite are common at all doses but typically improve within days to weeks

Dosing paradigms, route of administration, and exposure considerations Published in vivo experiments commonly use intraperitoneal (i.p.) administration at 50 mg/kg twice daily for 1228 days in adult male C57BL/6J or ob/ob mice, with cohorts kept at thermoneutrality and studied by indirect calorimetry (CLAMS) and body-composition analyses

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