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View Study Bhasin, S., et al
Most clinical evidence linking GLP-1 use to IBS improvement comes from observational data rather than randomized controlled trials, meaning causality cannot be definitively established
Phase 3 Development & Timeline Orforglipron's Phase 3 clinical development program is one of the most comprehensive in the history of obesity and diabetes pharmacotherapy, encompassing multiple trials across two parallel programs: the ATTAIN series for obesity indications and the ACHIEVE series for type 2 diabetes
[12] Hursel R, Viechtbauer W, Westerterp-Plantenga MS
If left untreated, pancreatitis can lead to serious complications, including organ failure
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