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Given the complexity of its dual mechanism of action as a GIP and GLP-1RA, tirzepatide, hence defined as twincretin [75], is a key innovation in the MASLD armory [76]
It is typically considered for people with a BMI of 40 or higher or those with a BMI of 35 or higher who have obesity-related health problems
The medication comes in a pre-filled pen, making it easier for patients to administer their doses accurately
Beyond-use dates versus expiration dates Brand-name medications have expiration dates assigned by the manufacturer based on years of stability testing under controlled conditions
The randomization schedule remained blinded to the sponsor, participants, investigator, and site staff, from the time of participant screening to the final data lock
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