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This was evident in the LIVE and FIGHT trials, in which liraglutide, despite leading to significant weight loss compared with placebo, failed to demonstrate any beneficial effects on clinical outcomes or left ventricular ejection fraction (LVEF) in patients with HFrEF

Elevated GH levels can result in complications like acromegaly, a condition characterized by excessive growth of tissues and organs

Slowed gastric emptying and disrupted digestive enzyme activity can contribute to subclinical malabsorption

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We extended the analysis to human PBMCs, CD14 + monocytes, macrophages, and PMA-differentiated THP-1 cells and detected basal expression in all (Fig