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Kastenmller are co-inventors (through Duke University/Helmholtz Zentrum Mnchen) on patents on applications of metabolomics in diseases of the central nervous system and hold equity in Chymia LLC and IP in PsyProtix and Atai that are exploring the potential for therapeutic applications targeting mitochondrial metabolism in treatment-resistant depression
Such properties possibly make ketogenic therapy valuable for optimising BC in obesity treatment [135]
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Existing research is often hampered by small sample sizes, inadequate control groups (making comparisons difficult), and lack of publication in reputable journals
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