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The honest summary is that topical GHK-Cu has a favorable tolerability profile for most users, but individual responses vary and rigorous large randomized trials specifically powered to detect rare harms are lacking
Severe gastrointestinal conditions: Those with delayed gastric emptying, gastroparesis, or chronic GI dysmotility may experience exacerbated symptoms due to the drugs action on gastric motility
GHK-Cu is easier to evaluate scientifically: you can match the label to one compound, one molecular identity, and a cleaner COA expectation
Won H, Huang J, Opland CK, Hartl CL, Geschwind DH (2019) Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility
AHK-Cu and GHK-Cu are copper peptides that support skin and scalp -they do not block DHT
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