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Altered gut motility these medications affect the movement of the entire gastrointestinal tract, not just the stomach

In additional secondary endpoints, retatrutide reduced known markers of cardiovascular risk, including non-HDL cholesterol, triglycerides, and high-sensitivity C-reactive protein (hsCRP), and at the highest dose lowered systolic blood pressure by 14.0 mmHg, using the efficacy estimand

Consume with plenty of water