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Abstract Nutraceuticals represent promising strategies for preventing, delaying and addressing premature aging of the skin, especially as women advance in years (particularly after 30 years of age, when estrogen levels begin to decline, and remarkably after menopause when estrogen production ceases from the ovaries)

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found that epidermis-specific Mll4 -knockout mice developed red, scaly skin (Egolf et al., 2021)

Autophagy plays a crucial role in maintaining mitochondrial quality by degrading damaged organelles, thereby supporting cell survival [44]