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ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades ( Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis
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After 24 h, treated biofilms supernatant washed once with 1 PBS
Rosen has no relevant duality of interest to disclose
Scalp pain, burning, or itching accompanying the hair loss may indicate an inflammatory condition such as scarring alopecia, which can cause permanent follicular damage if not treated promptly
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