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Several biological pathways are being studied, though they likely do not all contribute equally in clinical practice

JAMA 327(2):138150 Bergmann NC et al (2023) Semaglutide for the treatment of overweight and obesity: a review

It was first identified in human plasma and has since become a major subject of interest in regenerative biology, tissue engineering, and extracellular matrix research

5l) and showed a dose-dependent effect (Fig