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Wang et al., 2008
PMID 9546215
Protein signals released after macrophages engulf lipid debris prompt fibroblasts to secrete large amounts of Type I collagen
Yes, the melanocortin family is quite broad
For instance, semaglutide received FDA and EMA approval for cardiovascular risk reduction in patients with obesity in 2024, and Novo Nordisk are also targeting the use of semaglutide in patients with obesity-related heart failure and metabolic associated steatohepatitis (MASH, formerly known as fatty liver disease)
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