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Previous studies have demonstrated that inhibition of Panx1 decreases MDA levels in I/R-induced AKI 338 , In AKI caused by rhabdomyolysis, destruction of striated muscle cells leads to the release of large amounts of myoglobin into the blood, which is the main factor leading to kidney injury 339

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PubMed Korkushko OV, Khavinson VK, Shatilo VB, Antonyuk-Shcheglova IA