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445 participants: 12 mg: average 28.7% body weight loss WOMAC knee pain scores dropped by up to 75.8% More than 1 in 8 patients became completely pain-free Systolic blood pressure improved by 14.0 mmHg TRANSCEND-T2D-1 Type 2 diabetes (40 weeks) Published March 2026

If the clinical notes frame the treatment as improving appearance, energy, or general wellness without connecting it to a diagnosed condition, the claim fails

Prolonged accumulation of lipids in hepatocytes is associated with lipotoxicity, which may initiate inflammation, apoptosis and ultimately fibrosis (21)

But shaking creates foam at air-liquid interfaces, and proteins (including peptides) denature at these interfaces

A Functional Medicine Interstitial Cystitis Protocol: Testing, Nutrition, and Supplements