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Excessive pro-inflammatory cytokines suppress the negative feedback of the HPA axis, boost the permeability of the blood-brain barrier, decrease the synthesis of neurotransmitters such as serotonin (5-HT), and ultimately lead to the onset of depression (Haroon and Miller, 2017

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Employer Benefits: Data on employer-provided coverage for GLP-1 agonists came from the KFF 2025 Employer Health Benefits Survey

Moreover, the duration of the treatment being carried out, that is a number of sessions one takes and the aftercare also impacts the efficacy of the treatment

Appetite rebounds, often exceeding pre-treatment levels in the short term