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Defects in OCTN2 causes primary systemic carnitine deficiency presenting with cardiomyopathy and often myopathy and/or hepatic encephalopathy in early childhood, and is a treatable condition

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J Pharmacol Sci 108:227238 Massucci FA, DiNuzzo M, Giove F, Maraviglia B, Castillo IP, Marinari E, De Martino A (2013) Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective

Quantification of glutathione concentration Assays were performed on brain tissue and plasma samples using the GSSG/GSH Quantification Kit (Dojindo, Kumamoto, Japan )

The authors concluded that VC is a new type of collagen without animal sources that is sustainable and natural as an active ingredient in oral supplementation treatments to improve skin health, along with being environmentally friendly [50]