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A 180-pound person needs at least 90 ounces, about 2.6 liters
10.1074/jbc.M502862200 J
192-194 However, the combined effect of smoking and sleep apnea has been linked to worse cognitive impairment and metabolic parameters
There is no established safe and effective dose for astaxanthin, but daily doses between 4 mg and 18 mg have shown some benefits without reported side effects in clinical studies, although long-term studies are needed (See ConsumerTips)
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