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Interatomic contacts and hydrogen bonds were detected using the GetContacts scripts tool ( setting a hydrogen bond donor-acceptor distance of 3.3 and an angle value of 120 as geometrical cut-offs
That combined action is the mechanistic feature that separates it from semaglutide-class molecules, and it is the reason the compound is often discussed on its own rather than lumped in with single-target agonists
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Can J Gastroenterol Hepatol
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