This faster relaxation occurred without significant changes in other key parameters, including resting tension, maximal tension, the rate constant of tension development ( k ACT ), tension redevelopment ( k TR ), the duration of linear relaxation ( t REL, LIN ), the rate constant of exponential relaxation ( k REL, EXP ), sarcomere length, or calcium sensitivity ( Figure S2 )
Precision matters more than volume
More importantly, semaglutide and tirzepatide are not interchangeable on a milligram-for-milligram basis
We know what the weight loss is with drugs and with surgery. In the US, bariatric or metabolic surgery is recommended for patients with a body mass index (BMI) 35 kg/m 2 regardless of the presence, absence, or severity of comorbidities and for patients with obesity (BMI 30 kg/m 2 ) and type 2 diabetes
doi: 10.1016/j.lfs.2020.118398 12 KapitzaCDahlKJacobsenJBAxelsenMBFlintA