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The green dashed line indicates the predicted cleavage site (CS)

While theres no evidence that expired semaglutide breaks down into something harmful, its impossible to predict how it might behave once its passed the expiration date manufacturers can only guarantee its safety and effectiveness up to the date on the label

The city pushed for the change last week, arguing it faces steep increases in its health care costs driven, in part, by a spike in city workers using GLP-1 drugs

They come from different populations, different treatment durations, different placebo runs, and different statistical estimands (for example, the efficacy estimand that assumes continued treatment versus the treatment-regimen estimand that counts discontinuations)

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