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Tirzepatide may also cause additional stomach issues such as constipation, belching, indigestion, and fatigue, and there is a possible risk of low blood sugar, especially when combined with other diabetes medications

Malhotra adds that long-term cost-effectiveness should be evaluated, asking, Is it worth it to put people on these medications, or are there cheaper ways of achieving that same results, which, right now, I dont know what that would be

Analysts have suggested that approval in CSU alone could make the drug a blockbuster, with sales of more than $1 billion a year, and Novartis is running phase 3 trials for chronic inducible urticaria (CINDU) and multiple sclerosis (MS), and phase 2 studies in hidradenitis suppurativa (HS) and food allergy indications