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Moreover, in the hypothyroid animals, many of the mast cells showed partial or complete degranulation, which was in contrast to the non-activated mast cells in the animals with normal thyroid function.[ref] Other animal studies show that hypothyroidism increases mast cell infiltration into the liver and mast cell levels in the bone marrow
Beyond being frustrating on a personal level, those changes can create tension, confusion, and stress in even the strongest relationships
Patients often report that they did not realize how poor they felt until B12 began to help their bodies
Common adverse effects include gastrointestinal symptoms (nausea, vomiting, diarrhea, constipation), which are usually transient and dose-dependent
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