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Genetic variants in NAT2, GST, and CYP2E1 influence metabolic rates but don't predict toxicity alone

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From Rat Studies to Human Extrapolation From rat studies, the remarkably consistent effective dose range of 0.0045 mg/lb to 0.0000045 mg/lb intraperitoneally (a 1000-fold range showing similar efficacy) worked across depression, anxiety, Parkinsons, stroke, schizophrenia, and seizure models

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They report obvious narratives of reduced hunger, fewer snacks, and not constantly thinking about food

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