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Figure 1 Discussion To the best of our knowledge, this is the first clinical study in ME/CFS patients describing a novel administration route of vitamin B12

For constipation: increase fiber intake gradually, stay hydrated, and maintain physical activity

Additionally, because NAC possesses mild blood-thinning properties by breaking disulfide bonds in clotting factors, taking it alongside anticoagulants or antiplatelet drugs can increase the risk of bruising and bleeding

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These amino acids and peptide fragments can then be absorbed and used by the body to build, repair, and regulate different tissues and systems