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however, in reducing iron deposition, baicalein is superior to deferrioxamine and its mechanism may be related to the up regulation of hepcidin and its regulators bone morphogenetic protein 6 (BMP-6), SMAD family member 4 (SMAD4), and transferrin receptor 2 (TfR2) at the protein and mRNA levels ( Baicalin Baicalin is the 7-hydroxyl group of baicalein, followed by glucuronide

The study by Ruggeri et al

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This method bypasses the digestive system, allowing for immediate absorption and utilization by the body