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In-vitro studies show both GHK and GHK-CU increase fibroblast activity that enhances the production of collagen, elastin, fibronectin, and other extracellular matrix components

Reed, D.J

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Treatment with the proline derivative, particularly at the 200 mg/kg dose, significantly reversed these alterations, restoring biochemical parameters to near-normal levels, comparable to the standard hepatoprotective agent, silymarin (Tables 5 and 6)