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10.3389/fnins.2015.00037 38
The trade-off is clear: you sacrifice the speed and magnitude of weight loss seen in clinical trials at higher doses in exchange for a more tolerable experience and a protocol that is easier to sustain over time
31,35-37 Prospective trials are needed to further explore this potential adverse event and worsened DR, which is the central premise of the ophthalmic FOCUS trial that is expected to release results in 2026
1994 Fall;15 Lushchak VI
NNMT participates in nicotinamide metabolism through this activity
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