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This reaction is temperature-dependent and essentially irreversible once it occurs

doi:10.1002/nbm.4227 112. Shimizu, T., Iwanaga, M., Yasunaga, A., Urata, Y., Goto, S., Shibata, S., & Kondo, T

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In SAH, early brain injury (EBI) is crucial, indicating the pathological damage within 3 days after SAH ( Several animal models were adopted for hemorrhagic stroke research