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many remain on a stable maintenance dose after reaching their target
Semaglutide (Ozempic, Wegovy) is a GLP-1 receptor agonist that must be refrigerated at 36F to 46F (2C to 8C) before first use to maintain its effectiveness
If your dose calculates to 16.7 units, round to 17 units (rounding up by 0.3 units delivers an extra 0.015 mg at 5 mg/mL, clinically irrelevant)
These therapies aim to enhance WL and improve metabolic outcomes by engaging multiple hormonal pathways, with preclinical and early-phase clinical trials supporting their potential as next-generation obesity treatments [16,17,18,19,20,21,22,23]
Most common (especially in first 4-8 weeks): Nausea Early fullness/satiety Constipation Mild reflux or burping Less common but important: Severe nausea preventing adequate eating or drinking Gallbladder issues (rapid weight loss increases gallstone risk) Pancreatitis (rare, more common with high triglycerides or gallstone history) Dehydration The side effect no one mentions: Undereating
