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Some of these options include Contrave (Naltrexone HCL/Bupropion), Bupropion XL (Wellbutrin), and Metformin XR

therefore, FDA is continuing to look into this issue," a communication stated last year

Prescription medication requiring medical supervision Contraindicated in patients with personal or family history of medullary thyroid carcinoma or MEN2 Most common adverse events are gastrointestinal (nausea, diarrhea, vomiting) Dose escalation schedule important to minimize GI side effects Efficacy and Safety of the Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide in Patients With Type 2 Diabetes (SURPASS-1): A Double-Blind, Randomised, Phase 3 Trial , published in The Lancet (Rosenstock J et al., 2021

Any other effect can be considered as a pleiotropic, off-target effect, or in the case of unwanted actions, adverse effects ( Figure 1 )