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doi: 10.21037/tp-21-367 35

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Comet assays and -H2AX immunostaining revealed elevated levels of DNA damage in SARS-CoV-2-infected Huh7 or Vero-6 (African green monkey kidney) cells (66, 190, 284, 285), but also in lymphocytes and cardiac tissue of deceased COVID-19 patients (286288)

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These findings agree with several previous studies, where gut microbiome diversity remained unaltered following GLP-1 receptor agonist or SGLT-2 inhibitor consumption throughout the treatment period 18,19,20

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