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In contrast, the pharmacological nanomolar concentrations of GLP-1RAs predominantly activate the cAMP/PKA pathway, potentially explaining their broader therapeutic effects [122]

Hence, the nanomaterials employed to improve clinical efficacy with plant-based therapeutic agents have proven to be the most effective approach to overcome pharmacokinetic and biopharmaceutical hindrances (Dewanjee et al., 2020)

Clinical effect of antioxidant glasses containing extracts of medicinal plants in patients with dry eye disease: a multi-center, prospective, randomized, double-blind, placebo-controlled trial

in Journal of Nutrition vol