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Estriol-containing formulas (Biocosmetic Cream, Biocosmetic + SNAP-8, Methylene Blue Cream) are flagged for provider review in patients with hormone-sensitive cancer history and are a hard contraindication in pregnancy or breastfeeding

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Individual results vary, and no therapy should be started without an evaluation by a qualified healthcare provider

In fact, the US Anti-Doping Authority says there is a concerning lack of published clinical trial data because studies appear to have been cancelled or stopped without any published conclusions

There have been rare reports of probiotic-related bacteraemia and fungaemia in critically ill or immunosuppressed patients, though such cases remain exceptional