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Then there is the hormonal component

BMC Pediatr (2022) 22:632

There is no confirmed direct chemical interaction between semaglutide and weed, yet behavioural and physiological effects may overlap in ways that influence treatment outcomes

Late responders are real

Studies have described that flavonols and their derivatives are likely the substrate for GSTLs, which tightly bind to these small molecules ( Arabidopsis and wheat Lambda class GSTs ( AtGSTL1, TaGSTL1 , and TaGSTL3) have been identified to be localized in cytosol, whereas others ( AtGSTL2 and TaGSTL2) are chloroplast localized (Theodoulou et al., 2003)