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People with diabetic gastroparesis need especially careful titration and monitoring
Kumar U (2012) Immunohistochemical distribution of somatostatin and somatostatin receptor subtypes (SSTR15) in hypothalamus of ApoD knockout mice brain
By mimicking these hormones, the drug does the following: Increases insulin secretion, resulting in lower blood sugar Decreases glucagon production (For those with diabetes, unchecked glucagon production can result in blood sugars that are too high.) Slows gastric emptying (process by which the contents of the stomach are emptied into the duodenum, the first part of the small intestine)
Key takeaways Zepbound (tirzepatide) can cause stomach pain
K., Forsting, M., Sartor, K., Adams, H
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