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Cortisol is a hormone that is released by the adrenal gland in response to stress, and it plays a role in a number of physiological processes, including glucose metabolism and immune system function

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[25] Cancer [edit] In response to a report of precancerous changes in the pancreases of rats and organ donors treated with the DPP-4 inhibitor sitagliptin, [26] [27] the US FDA and the European Medicines Agency each undertook independent reviews of all clinical and preclinical data related to the possible association of DPP-4 inhibitors with pancreatic cancer

Journal of immunology (Baltimore, Md : 1950) 189:36572

If we notice mole changes, we should contact a doctor