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It mainly promotes local or overall fat loss by stimulating fat breakdown and inhibiting fat synthesis
But the data strongly suggest that stopping without a transition plan significantly increases the probability of rapid weight regain and metabolic deterioration
My clinical recommendation is the same as for orforglipron: do not wait if you can safely start treatment today
These findings suggest a synergistic network of neuroprotective signalling, with GLP-1 and GLP-2 able to enhance or trigger VIPs protective actions
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