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15,16 As such, the DPP-4 inhibitors are generally considered weight neutral antihyperglycemic medications

The highest dose of Eli Lillys once-daily treatment helped patients lose about 12.4% of their body weight in a late-stage trial, well below analyst expectations of 15%, according to FactSet

Many doctors anticipate that the medication may be FDA approved sometime in 2027, Siegel says

Doctors have described them as game changers in obesity treatment, and some people using the drugs who've struggled with obesity have said they've never felt better