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The original $1,000 cash price of FDA-approved GLP-1 products (now selling for as low as $300 to $350 without insurance) naturally led patients toward compounded versions, which are advertised online for as little as $150 per month

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The guidelines warn, however, that GLP-1 receptor agonist therapy is not indicated for all patients and should be used with caution in patients with a history of significant gastrointestinal disease, such as a diagnosis of gastroparesis, due to a possible exacerbation of the condition with incretin mimetic therapy

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