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Cell culture Huh-7 cells were obtained from the National Collection of Authenticated Cell Cultures and cultured in Dulbeccos modified Eagle medium (DMEM

Chronic kidney disease (CKD) remains a significant driver of mortality and morbidity globally (Bello et al., 2022) despite a growing number of therapeutic options to stall progression (Mark et al., 2025)

doi: 10.1080/00498250010021684, 21

Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin diabetes control and potential adverse events

Studies have shown that patients using GLP-1 receptor agonists, alongside lifestyle modifications, can achieve an average weight reduction of 1015% of their body weight over time with improvements in blood sugar control, blood pressure, and cholesterol levels