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and Serlie, M

Kakavand H, Crainic O, Lum T, O'Toole SA, Kefford RF, Thompson JF et al

Tirzepatide activates both GLP-1 and GIP receptors, engaging broader appetite-regulation pathways than semaglutide alone

Available at: Last updated: October 2013

The N-terminal domain adopts the typical TRX-fold (with 1122343 topology) and the C-terminal domain is a bundle of at least five helices (4 to 8) (Figure 1)