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as a key regulator of mitochondrial biogenesis, PGC1 enhances mitochondrial function in myoblasts, supplies sufficient energy for differentiation, and regulates the transcription of myogenic genes to accelerate myotube maturation
The same biological mechanism (i.e., GLP-1 receptor agonism) now underpins semaglutide, sold under the names Ozempic, Mounjaro and Wegovy arguably the most culturally significant drug class of the past decade
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