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As it was previously demonstrated that lysine lactylation was induced by neural excitation, a key molecular mechanism for the development of epilepsy [96], with the detailed results showing the positive association of increase of lysine lactylation and the expression of the immediate-early gene marker of neuronal activity c-Fos [97], it is hypothesized that histone delactylation by HDAC1-3 may inhibit the development of epilepsy and prevent seizures

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biology 10(11):1165 Ugar M, Tufan AN, Altun M, Guclu K, Ozyurek M (2018) Glutathione peroxidase activity of biological samples using a novel microplate-based method

These findings add a new perspective on metabolic control to supplement the multifaceted roles of DDX3X in regulating cancer progression

This does not mean MOTS-c is more dangerous