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Multiple randomized controlled trials have shown that combining metformin with GLP-1 receptor agonists produces superior weight loss and HbA1c reduction compared to either medication alone

GLP-1 receptor agonists in the treatment of type 2 diabetes: role and clinical experience to date

Trulicity activates the GLP-1 receptor, helping your body lower blood glucose by increasing insulin release when blood sugar is high, reducing how much glucose the liver produces, slowing stomach emptying, and helping you feel fuller sooner

The black market for weight-loss injections is already well established, with the MHRA seizing thousands of doses being illegally manufactured and sold online