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MC3/4R activation reduces food intake in rodent models, though the effect tolerates with repeated dosing

This is because the medication is no longer there to keep reducing your hunger levels

Medical history review: Contraindications (pregnancy, active cancer, certain medical conditions) are identified before prescribing

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Each component of CS10 has its own clinical program: semaglutide in the STEP (obesity) and SUSTAIN (type 2 diabetes) studies, and cagrilintide in a dose-finding phase 2 study in obesity