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The remaining 25 articles were included in the qualitative synthesis, and 16 in the quantitative synthesis (Figure 1)

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For those with certain medical conditionssuch as pernicious anemia or gastrointestinal disorders that impact nutrient absorptionB12 shots are often the most reliable way to maintain healthy levels and support immune function

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Pernicious anemia tongue changes: I mentioned above in the symptoms that there could be changes to the tongue, called glossitis

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Allergies to vitamin B12 are extremely rarerarer than common allergies like bee stings, peanut butter, or shellfish

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In cases of documented vitamin deficiency, the regimen could be an initial intensive phase (like 2 mL IM three times a week for 2 weeks) followed by reevaluation

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