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Second, persistent inflammation at a single site can cause lipoatrophy or lipohypertrophy over time, which impairs drug absorption and introduces dose unpredictability

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All diagnoses on the TriNetX medical database are classified by the International Classification of Diseases (ICD), Tenth Revision, Clinical Modification (ICD-10-CM) code set, which is a modified version of the World Health Organization ICD, Tenth Revision, standard

A: Appetite changes can appear within the first weeks, especially during titration

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