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Limited evidence suggests it may help with modest blood sugar regulation after meals

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Triplehormone-receptor agonist GLP-3 (Reta) for obesity a phase 2 trial

Semaglutide trials showed an average weight loss of approximately 15%, indicating that the medication alters baseline physiology but typically requires ongoing support to sustain results

These medications should be avoided by people who are pregnant or breastfeeding, those with a history of pancreatitis, and anyone with a personal or family history of medullary thyroid cancer or MEN2 syndrome