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In a post hoc analysis of the SURPASS-1 trial involving patients with T2DM, the percentage increase in adiponectin levels from baseline ranged from 16% to 23% with tirzepatide compared to a decrease of 0.2% with placebo at week 40 (190)
While Wegovy and Ozempic both contain semaglutide, Wegovy is FDA-approved for weight loss, whereas Ozempic is approved for blood sugar control, Ngo said
Tang et al., 2019)
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If those underlying drivers are not addressed, no peptide, no supplement, and no treatment will ever deliver what it is capable of delivering
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