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This randomized controlled trial suggests that vitamin B12 supplementation may improve homocysteine levels and metabolic markers in patients with liver disease, with modest effects on liver health

In the normal saline control group, hepsin / mice showed a 1.5-fold increase in hepatocyte Cx32 expression relative to the wild-type control group

Based on our data, we believe that the RESILIENCE trial would have achieved better outcome for the patients if it were designed to treat HR+ patients with Sorafenib together with hormonal therapy versus Placebo with hormonal therapy

GH-mediated downstream effects (hepatic IGF-1 production, anabolic signaling) are the proposed basis for claimed metabolic benefits, but the evidence base is limited to animal and in vitro research

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