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Doses above 1,000 mg/day have a weaker safety profile and a higher probability of GI overlap with tirzepatide
Wirth, F
Key Takeaways: GLP-1s Or Bariatric Surgery For Weight Loss Bariatric surgery procedures restrict stomach size or reduce hunger hormones to help patients lose weight
Tirzepatide (Mounjaro, Zepbound) is an FDA-approved dual GIP/GLP-1 receptor agonist for type 2 diabetes and chronic weight management, while multiple sclerosis is a chronic autoimmune disorder affecting the central nervous system
Cardiovascular outcomes trials (SUSTAIN-6, SELECT) demonstrate that long-term use reduces heart attack and stroke risk in people with obesity and existing heart disease
